A 5-year-old girl is brought to her pediatrician because her mother says she is frequently bumping into stationary objects while playing. Visual field examination shows bilateral peripheral vision defects. CT of the head reveals calcifications in the pituitary fossa. Which of the following is the most likely origin of this child’s brain tumor?
一个5岁的小女孩被带到她的儿科医生那里,因为她的母亲说她在玩耍时经常撞到固定的物体。视野检查显示双侧周边视力缺损。头部CT显示垂体窝内钙化。以下哪一项是这个孩子脑瘤最可能的起源?
(A) Adenohypophyseal lactotrophs 腺垂体乳滋养细胞
(B) Fourth ventricle neuroectoderm 第四脑室神经外胚层
(C) Rathke pouch Rathke囊
(D) Vascular endothelium 血管内皮
(E) Ventricular lining 心室壁
答案解析:
所描述的视野缺损是双颞侧偏盲,典型的原因是蝶鞍的病变撞击视交叉。在儿童中最常见的肿瘤是鼻咽管瘤,来源于Rathke囊的残留物。这个胚胎结构从口腔顶部发芽形成垂体前叶。双颞侧偏盲通常伴有严重头痛和垂体功能低下。治疗包括手术、放疗或两者兼而有之。
正确答案:C
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