临床研究
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JAMA Network Open:早期脓毒症所致低血压的外周升压药应用
Abstract Importance: Evidence supporting the safety of infusing vasopressors through perip…
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JAMA:左西孟旦促进严重心源性休克患者脱离体外膜肺氧合（ECMO）的LEVOECMO随机临床试验
Abstract Importance: Levosimendan may facilitate weaning from venoarterial extracorpo…
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CC:心脏骤停后结果预测的自动灰质-白质比纵向评估
Abstract Background The gray-white matter ratio (GWR) on head CT is a well-established mar…
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NEJM Evidence:急性胸综合征预测评分的验证与应用
背景：血管闭塞危象（VOC）是镰状细胞病最常见的表现，而急性胸综合征（ACS）是其常见并发症，具有较高的死亡风险。本研究的目的是验证先前开发的PREdictive SEVerity…
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CC:降钙素原轨迹作为识别高死亡风险脓毒症患者的有效工具
脓毒症是一种严重疾病，对全球医疗系统造成沉重负担。鉴于脓毒症患者之间存在显著的异质性，识别高死亡风险群体至关重要[1]。降钙素原（PCT）是一种被广泛认可的评估脓毒症严重程度并指导…
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ICM:利用生命体征轨迹构建和验证脓毒症新亚型
Abstract Purpose: Sepsis is a heterogeneous syndrome and identification of sub-phenotypes …
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JAMA：七天与四天更换输液器间隔及导管相关感染的比较
Abstract Importance: Catheter-related bloodstream infections (CRBSIs) are associated …
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CCM:静脉-动脉体外膜肺氧合期间的神经系统并发症及其对6个月以患者为中心结局的影响
Abstract Objectives: Venoarterial extracorporeal membrane oxygenation (ECMO) is assoc…
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JAMA:低分子肝素联合胰岛素治疗高甘油三酯血症性急性胰腺炎：一项随机临床试验
Abstract Importance: Although insulin is widely used for early lipid lowering in hypertrig…
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CCM：达到目标体温的时间对心脏骤停幸存者是否重要？一项系统综述与荟萃分析
Abstract Objectives: To identify the impact of early hypothermic temperature control …
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ICM:澳大利亚和新西兰重症成人中脓毒症和感染性休克的死亡率趋势
Abstract Purpose Sepsis is a major cause of mortality in intensive care unit (ICU) patient…
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ICM:衰弱对院外心脏骤停后死亡率、功能结局及健康状况的影响：来自TTM2试验的见解
Abstract Purpose: To explore the association of frailty with mortality, functional ou…
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CCM:脓毒性休克中亚甲蓝的应用：一项回顾性队列研究
Abstract Objectives: To describe the epidemiology of methylene blue (MB) use in septic sho…
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Int J Surg：去甲肾上腺素-苯肾上腺素与去甲肾上腺素-血管加压素在感染性休克中的临床结局比较：一项回顾性队列研究
Abstract Purpose: This study aims to compare the clinical outcomes of norepinephrine …
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JAMA Netw Open：利用大语言模型对脓毒症队列进行综合征分析
Abstract Importance: Presenting signs and symptoms affect the care of patients with p…
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Respiratory Research：开发并多数据库验证用于预测肺炎患者院内死亡率的可解释机器学习模型：一项横跨四个医疗系统的综合分析
Abstract Background: Existing machine learning studies for pneumonia mortality predic…
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JAMA:脓毒性休克中氢化可的松与肾脏替代治疗风险因素的关系
Abstract Importance: Sepsis-associated acute kidney injury (SA-AKI) is a common and c…
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JAMA:碳酸氢钠治疗严重代谢性酸中毒和急性肾损伤
Abstract Importance: The effect of sodium bicarbonate infusion on outcome in patients with…
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NEJM:休克患者动脉置管，真的非做不可吗？
Abstract Background: In patients with shock, whether noninvasive blood-pressure monitoring…
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CC:特利加压素辅助治疗难治性脓毒性休克与安慰剂的比较：一项随机、安慰剂对照试验
Background Terlipressin’s role as an adjunctive vasopressor in septic shock remains contro…
