临床研究
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NEJM:血流储备分数和血管内超声成像指导PCI的比较
Abstract Background: In patients with coronary artery disease who are being evaluated for …
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NEJM:PCI后高危患者接受常规功能检测和标准治疗的比较
Abstract Background: There are limited data from randomized trials to guide a specifi…
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NEJM:心脏停搏后昏迷幸存者的血压目标
BACKGROUND Evidence to support the choice of blood-pressure targets for the treatment of c…
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NEJM:心脏停搏后昏迷幸存者的氧合目标
BACKGROUND The appropriate oxygenation target for mechanical ventilation in comatose survi…
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NEJM: 经皮血运重建术治疗缺血性左心室功能不全
BACKGROUND Whether revascularization by percutaneous coronary intervention (PCI) can im- p…
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BMJ:新型冠状病毒肺炎后深静脉血栓形成、肺栓塞和出血的风险:全国性自身病例对照系列和配对队列研究
AbstrAct Objective To quantify the risk of deep vein thrombosis, pulmonary embolism, and b…
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NEJM: COVID-19住院患者的治疗剂量肝素抗凝
COVID-19患者有发生血栓形成的风险。为了改善患者临床结局而应用治疗剂量肝素的安全性和效果尚不明确。短视频中总结了新的研究发现。
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NEJM: 非心脏手术患者使用氨甲环酸
Abstract BACKGROUND Perioperative bleeding is common in patients undergoing noncardiac sur…
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ICM:G试验指导的脓毒症患者抗真菌治疗
Abstract Purpose: To investigate whether (1 → 3)‐β‐d‐Glucan (BDG)‐guidance shortens time t…
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NEJM:脓毒症患者ICU输液的限制
BACKGROUND Intravenous fluids are recommended for the treatment of patients who are in sep…
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NEJM:静脉维生素C治疗ICU中脓毒症成年患者
Abstract BACKGROUND Studies that have evaluated the use of intravenous vitamin C in adults…
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单剂两性霉素B脂质体治疗隐球菌性脑膜炎
隐球菌性脑膜炎的治疗方案通常包括为期1周的两性霉素B脱氧胆酸盐静脉给药治疗。然而,该疗法有很大的毒性风险,因此有必要开发更安全的替代疗法。短视频中总结了新的研究发现。
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BMJ: 合并中度低氧血症的新冠肺炎患者实施俯卧位
Abstract Objectives To assess the effectiveness of prone positioning to reduce the ri…
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NEJM: 急性大核心梗死卒中的血管内治疗
BACKGROUND Endovascular therapy for acute ischemic stroke is generally avoided when the in…
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P/FP比值: 将PEEP纳入PaO2/FiO2 Ratio用于ARDS的预测和分类
Abstract Background: The current Berlin definition of acute respiratory distress syndrome …
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ICM: 经胸超声和脓毒症的病死率:MIMIC-III期数据库分析_复现
Abstract Purpose: While the use of transthoracic echocardiography (TTE) in the ICU is rapi…
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Lancet Respir Med:通过机器学习使用临床数据区分ARDS亚表型的验证与应用
Summary Background Two acute respiratory distress syndrome (ARDS) subphenotypes (hyperinfl…
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JAMA: 多中心随机对照提示床旁即时CPR培训或无益于提升心脏骤停存活患儿神经系统转归
Abstract Importance: Approximately 40% of children who experience an in-hospital card…
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NEJM:对危重成人患者应用平衡多电解质溶液与生理盐水的比较
Abstract BACKGROUND Whether the use of balanced multielectrolyte solution (BMES) in prefer…