A 40-year-old nulligravid woman visits her gynecologist because of menstrual irregularities. She also recently started producing breast milk even though she is not nursing. A pregnancy test is negative. Which of the following recent medical diagnoses is most likely related to the patient’s symptoms? 一位40岁的女性因为月经不规律而去看妇科医生。她最近也开始分泌母乳,尽管她还没有哺乳。验孕结果为阴性。以下哪项最近的医学诊断最有可能与患者的症状有关?
(A) Menopause更年期
(B) Parkinson disease
(C) Schizophrenia精神分裂症
(D) Turner syndrome 特纳综合征
(E) Type 2 diabetes mellitus
答案解析:
患者极有可能有高泌乳素血症。泌乳素分泌增加解释了在近期无妊娠和哺乳的情况下泌乳。此外,由于催乳素抑制促性腺激素释放激素的合成和释放,患者月经不调。高泌乳素血症通常由肿瘤或抗精神病药物引起。抗精神病药是多巴胺拮抗剂,可导致催乳素分泌增加(多巴胺可抑制催乳素释放)。病人极有可能被诊断为精神障碍,如精神分裂症,需要多巴胺抑制。
正确答案:C
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