A 45-year-old man presented with a 2-month history of worsening pain and swelling in his right shoulder. He worked in construction and had chronic intermittent pain in the joint. An MRI showed destructive arthropathy of the glenohumeral joint associated with a large effusion, free-floating calcific fragments, and full-thickness tears of the rotator cuff tendons. Analysis of the synovial fluid revealed hemorrhagic, noninflammatory fluid with negative cultures and no visible crystals. What is the most likely diagnosis?
一名45岁男性患者因右肩疼痛和肿胀加重2个月就诊。他从事建筑工作,且该关节长期存在间歇性疼痛。MRI显示盂肱关节破坏性关节病变,伴有大量关节积液、游离的钙化碎片以及肩袖肌腱全层撕裂。滑液分析显示为出血性、非炎性液体,培养结果阴性,且未发现可见晶体。最可能的诊断是什么?

A. Avascular necrosis of the humeral head肱骨头缺血性坏死
B. Calcium pyrophosphate deposition disease焦磷酸钙沉积病
C. Joint sarcoma关节肉瘤
D. Milwaukee shoulder syndromeMilwaukee肩综合征
E. Rotator cuff tear arthropathy肩袖撕裂性关节病
答案解析:
Milwaukee肩综合征是一种破坏性关节病,其特征为羟磷灰石晶体沉积(这些晶体在光学显微镜下不可见)、肱骨头破坏以及严重的肩袖损伤。虽然该疾病最常见于65岁以上女性,但考虑到该患者因工作原因长期反复使用肩关节,以及可能存在的既往肩袖损伤,因此认为其发生该疾病的风险增加。
正确答案:D
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