A 30-year-old man presented with a 6-month history of depressed skin lesions on his back. On physical examination, numerous well-defined, erythematous, atrophic plaques were noted across the back. A fluorescence staining preparation of skin scrapings showed thick fungal hyphae and yeast cells with a “spaghetti and meatballs” pattern. What is the most likely causative organism for this skin infection?
一名30岁男性患者出现了背部皮肤凹陷性病变,持续6个月。体格检查时,背部可见许多界限清楚、红斑性、萎缩性斑块。皮肤刮片荧光染色显示有厚的真菌菌丝和酵母细胞,呈现“意大利面和肉丸”模式。这种皮肤感染最可能的致病微生物是:
A. Candida species念珠菌属
B. Epidermophyton species表皮癣菌属
C. Malassezia species马拉色菌属
D. Microsporum species小孢子菌属
E. Trichophyton species发癣菌属
答案解析:
皮肤刮片荧光染色上的“意大利面和肉丸”模式与马拉色菌感染一致。诊断为萎缩性花斑癣。花斑癣是由马拉色菌属的共生真菌引起的皮肤病。该病也被称为色素减退性癣,尽管它不像体癣或足癣那样是由皮肤癣菌引起的。花斑癣通常表现为躯干上的色素沉着或色素减退性斑块。这些病变也可能是红斑性的,或者在极少数情况下,如本病例,是萎缩性的。
正确答案:C
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