A 54-year-old woman presents to her physician with swelling in her extremities. Palpation produces significant pitting. Which of the following conditions represents the most likely physiologic basis for this physical finding? 1例54岁女性因四肢肿胀就诊。触诊有明显的凹陷。以下哪种情况是该体格检查结果最可能的生理学基础?
(A) Decreased capillary permeability 毛细血管通透性降低
(B) Decreased capillary pressure 毛细血管压降低
(C) Increased interstitial fluid pressure 间质液压力升高
(D) Increased interstitial oncotic pressure 间质胶体渗透压升高
(E) Increased plasma protein levels 血浆蛋白水平升高
答案解析:
净液体运动由公式JV = Kf[(Pc−Pi)-(pc−pi)] 控制,其中 Kf 是滤过系数(考虑膜渗透性),Pc是毛细血管压,Pi是间质液压力,pc是毛细血管胶体渗透压,pi是间质胶体渗透压。毛细血管的Pc、pi或渗透性增加将导致液体从毛细血管净流入间质,导致该患者中观察到的水肿。同样,降低 pc 和 Pi 也将导致净外流和水肿。
正确答案:D
原创文章(本站视频密码:66668888),作者:xujunzju,如若转载,请注明出处:https://zyicu.cn/?p=14513