AIDS is currently managed with highly active anti-retroviral therapy, combining a series of medications to overwhelm the virus and minimize its ability to form resistance to any one of the medications. Currently, protease inhibitors, nucleoside reverse transcriptase inhibitors, and non-nucleoside reverse transcriptase inhibitors are three types of medications that can be used in combination. Which of the following is a non-competitive reverse transcriptase inhibitor?
艾滋病目前采用高效抗逆转录病毒疗法,联合使用一系列药物以压倒病毒,并将其对任何一种药物形成耐药性的能力降至最低。目前,蛋白酶抑制剂、核苷类逆转录酶抑制剂和非核苷类逆转录酶抑制剂是三种可以联合使用的药物。下列哪一种是非竞争性逆转录酶抑制剂?
(A) Didanosine
(B) Lamivudine
(C) Nevirapine
(D) Saquinavir
(E) Zidovudine
答案解析:
奈韦拉平是一种非核苷类逆转录酶抑制剂(NNRTI)。NNRTIs通过与逆转录酶结合并作为非竞争性抑制剂发挥作用。非竞争性抑制剂与酶活性位点以外的位点结合。
正确答案:C
原创文章(本站视频密码:66668888),作者:xujunzju,如若转载,请注明出处:https://zyicu.cn/?p=16038