A 68-year-old woman with type 2 diabetes mellitus and a 30-pound weight loss over the past two months presents to the physician with a history of nausea and bloating. Symptoms are most prominent following a meal. An outpatient gastric emptying study shows esophageal dysmotility. The best treatment option for this patient is which of the following?
一名68岁女性2型糖尿病患者因恶心和腹胀病史就诊,过去两个月体重减轻了30磅。饭后症状最明显。门诊胃排空检查显示食管运动障碍。该患者的最佳治疗方案是以下哪一种?
(A) Esophageal resection 食管切除
(B) Metoclopramide胃复安
(C) Omeprazole奥美拉唑
(D) Ondansetron昂丹司琼
(E) Vagotomy迷走神经切断术
答案解析:
该患者表现为胃轻瘫,尤其是继发于糖尿病的食管运动障碍。食管动力障碍的其他原因包括糖尿病性胃轻瘫、恰加斯病、狼疮和其他胶原血管疾病。初始治疗包括促动力药,甲氧氯普胺是一线治疗。
正确答案:B
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