每日一题_2023.12.21

A 25-year-old woman with severe obesity presented to the emergency department with a 1-week history of blurred vision, headaches, and transient visual obscurations. Neurologic examination showed optic disk swelling and retinal hemorrhages in both eyes. An MRI and MRV of the head showed flattened posterior globes, an empty sella, and stenoses of the transverse sinuses without obstruction or thromboses. Which abnormality would most likely be notable from a lumbar puncture?

一名25岁重度肥胖女性因视力模糊、头痛和一过性视觉模糊1周到急诊科就诊。神经系统检查显示双眼视盘肿胀、视网膜出血。头部MRI和MRV显示后球扁平，空蝶鞍，横窦狭窄，但无阻塞或血栓形成。腰椎穿刺最有可能出现的异常是什么?

A. Elevated opening pressure 压力升高

B. Elevated white blood cell count .白细胞计数升高

C. Oligoclonal bands 寡克隆区带

D. Positive anti-aquaporin 4 antibody 抗水通道蛋白4抗体阳性

E. Xanthochromia黄变症

答案解析：

腰椎穿刺显示开放压力升高，其他脑脊液分析正常。颅内压升高是特发性颅内高压的一个体征，特发性颅内高压是一种与肥胖相关的疾病，表现为颅内压升高引起的症状，包括头痛、复视和视野缺损。

正确答案：A