A previously healthy 26-year-old man presented with a 5-day history of fever, nausea, and vomiting and a 2-day history of an itchy rash. The rash had started behind his ears and then spread to his face and entire body. The patient was a refugee from a Middle Eastern country and had had limited vaccinations. Well-demarcated erosions were also present on the buccal mucosa on both sides of the mouth. What is the most likely etiology of these erosions?
一名既往健康的26岁男性患者,因发热、恶心、呕吐5天,伴瘙痒性皮疹2天前来就诊。皮疹最初出现在耳后,随后蔓延至面部及全身。患者为来自中东国家的难民,疫苗接种史有限。此外,双侧颊黏膜可见边界清晰的糜烂灶。这些糜烂最可能的原因是什么?

A. Aphthous ulcers阿弗他溃疡
B. Forchheimer spots福尔希海默斑点
C. Fordyce spots福代斯斑点
D. Herpes stomatitis疱疹性口炎
E. Koplik spots科普利克斑点
答案解析:
颊黏膜上的糜烂表现符合科普利克斑点(Koplik spots)。根据该患者的典型皮疹(exanthem)及口腔黏膜疹(enanthem),怀疑为麻疹。血清学检查显示抗麻疹 IgM 和 IgG 均阳性,进一步确诊了原发性麻疹感染;血液标本的麻疹病毒实时定量 PCR 检测亦为阳性。治疗上给予退热药物,患者在就诊两周后康复,无并发症发生。
正确答案:E
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