An 81-year-old woman with a history of hepatitis C virus–related cirrhosis and hepatocellular carcinoma, who was treated 9 days earlier with transarterial chemoembolization with the use of doxorubicin-eluting beads, presented with painful, progressively worsening skin lesions over the abdomen. A skin biopsy revealed epidermal necrosis and occlusion of small vessels in the reticular dermis. What is the most likely cause of the epidermal necrosis?
1例81岁女性患者，有丙型肝炎病毒相关肝硬化和肝细胞癌病史，9天前接受经动脉化疗栓塞联合阿霉素洗脱微球治疗，出现腹部疼痛性进行性加重的皮肤病变。皮肤活检显示表皮坏死和真皮网状层小血管闭塞。表皮坏死最可能的原因是什么？
A. Air Embolism 空气栓塞
B. Bacterial Embolism 细菌栓塞
C. Drug-Eluting Bead Embolism 药物洗脱珠栓塞
D. Cholesterol Embolism 胆固醇栓塞
E. Tumor Embolism 肿瘤栓塞
答案解析：
正确的答案是手术中使用的阿霉素洗脱微球栓塞。化疗栓塞材料扩散到肝动脉血管区域以外，或非靶栓塞，是手术的潜在并发症。患者接受口服己酮可可碱和外用糖皮质激素治疗，6个月时观察到病变改善但残留瘢痕。
正确答案：C
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