每日一题_2023.04.17

An 8-year-old boy presents to the clinic with a complaint of a runny nose and difficulty breathing. His mother says the boy has had recurrent respiratory infections, often with a productive cough. The child’s symptoms are tolerable in the morning, but seem to be- come progressively worse as the day continues. Chest auscultation reveals crackles and wheezing, but the physician is unable to auscultate a normal S1 and S2 heart sound. Radiographic examination reveals pulmonary hyperinflation, bronchiectasis, and a complete left/right reversal of his circulatory system. What other complication(s) is this patient likely to have?

一名8岁男孩因流鼻涕和呼吸困难到诊所就诊。他的母亲说，这个男孩反复出现呼吸道感染，经常咳嗽。孩子的症状在早上是可以忍受的，但随着时间的推移，症状会逐渐加重。胸部听诊显示有爆裂声和喘息声，但医生不能听诊正常的S1和S2心音。x线检查显示肺恶性膨胀，支气管扩张，循环系统完全左/右反转。这个病人可能有什么其他并发症?

(A) Flushing and diarrhea 潮红腹泻

(B) Infertility不孕症

(C) Panacinar emphysema 全腺肺气肿

(D) Pulsus paradoxus 奇脉

(E) Simple partial seizures单纯部分性癫痫

答案解析：

Kartagener综合征是一种遗传性疾病，由动力臂缺陷引起免疫纤毛。由这种缺陷引起的临床症状包括支气管扩张、复发性鼻窦炎和男女不育症。约50%的综合征患者出现逆位，通常没有严重的不良健康后果。

正确答案：B