每日一题_2022.06.09

A 67-year-old man presented with a 1-year history of bilateral eye swelling and right eye protrusion and a 2-week history of blurry vision. There was no swelling of the parotid or submandibular glands. MRI of the orbits showed bilateral lacrimal gland and lateral rectus muscle swelling as well as mass lesions surrounding the optic nerves. He was initiated on daily prednisone with improvement in his symptoms. What is the diagnosis?

每日一题_2022.06.09
NEJM June 09, 2022

A. IgG4-related ophthalmic disease 

B. Non-Hodgkin’s lymphoma 

C. Sjogren’s syndrome 

D. Tuberculosis-related dacryoadenitis 

E. Thyroid eye disease

答案解析:

正确的答案是IgG4相关的眼科疾病。血清IgG4水平升高,右泪腺活检标本显示IgG4阳性浆细胞淋巴浆细胞浸润。

正确答案:A

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