A 3-year-old girl was brought to the emergency department with a 2-month history of a white pupil and a 1-day history of redness and pain in the right eye. An eye examination showed leukocoria, as well as iris neovascularization and a white, nodular mass in the posterior chamber. The left eye was normal. B-scan ultrasonography showed calcification of the mass and vitreous seeding in the affected eye.
Which of the following is the most likely diagnosis?
A. Cataract
B. Coats’ disease
C. Ocular toxocariasis
D. Retinal detachment
E. Retinoblastoma
答案解析：
诊断为视网膜母细胞瘤。头部磁共振显示视网膜和脉络膜侵犯，无眼外扩展。鉴于高危临床特征，次日摘除眼球。组织病理学检查确诊。白瞳症需要眼科医生进行紧急评估，以便快速识别视网膜母细胞瘤等危及生命的原因。
正确答案：E
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